169120-56-3

169120-56-3 structure

169120-56-3 structure

Name: DP00477
Chemical Name: DP00477
CAS Number: 169120-56-3
Molecular Formula: C₁₇H₁₁ClF₃N₃OS
Molecular Weight: 397.80
Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
Create Date: 2023-01-14 23:46:31
Modify Date: 2023-01-14 23:46:31
DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer[1].

Name	DP00477

Description	DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
Target	IDO1:7.0 μM (IC50)
In Vitro	当添加 5 mM GSH 或 0.01% Triton-X 时，DP00477 对 IDO1 抑制性的 IC50 值分别为 71, 6.3 µM[1]。
References	[1]. Röhrig UF, et al. Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Eur J Med Chem. 2014 Sep 12;84:284-301.

Molecular Formula	C₁₇H₁₁ClF₃N₃OS
Molecular Weight	397.80