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169120-56-3

169120-56-3 structure
169120-56-3 structure
  • Name: DP00477
  • Chemical Name: DP00477
  • CAS Number: 169120-56-3
  • Molecular Formula: C17H11ClF3N3OS
  • Molecular Weight: 397.80
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
  • Create Date: 2023-01-14 23:46:31
  • Modify Date: 2024-09-27 12:16:18
  • DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer[1].

Name DP00477
Description DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer[1].
Related Catalog
Target

IDO1:7.0 μM (IC50)

In Vitro 当添加 5 mM GSH 或 0.01% Triton-X 时,DP00477 对 IDO1 抑制性的 IC50 值分别为 71, 6.3 µM[1]。
References

[1]. Röhrig UF, et al. Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Eur J Med Chem. 2014 Sep 12;84:284-301.  

Molecular Formula C17H11ClF3N3OS
Molecular Weight 397.80
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