1977557-97-3
1977557-97-3 structure
- Name: SC239
- Chemical Name: SC239
- CAS Number: 1977557-97-3
- Molecular Formula: C65H84N10O11
- Molecular Weight: 1181.42
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2023-01-14 19:18:17
- Modify Date: 2024-04-03 14:32:19
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SC239 is a cleavable 2-aminophenyl hemiasterlin drug-linker. SC239 can be as the drug-linker for ADC[1].
| Name | SC239 |
|---|
| Description | SC239 is a cleavable 2-aminophenyl hemiasterlin drug-linker. SC239 can be as the drug-linker for ADC[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | SC239 is composed of a tubulin-targeting 3-aminophenyl hemiasterlin warhead, SC209 (HY-144880), and a cleavable valine citrulline p-aminobenzyl carbamate linker functionalized with dibenzocyclooctyne (DBCO)[1]. The SC239 drug-linker is conjugated via a cleavable valine citrulline p-aminobenzyl carbamate linker functionalized with dibenzocyclooctyne (DBCO)[1]. SC239 conjugates exhibits better cytotoxic activity on Igrov1 cells which have lower expression levels of FolRα[1]. |
| References |
| Molecular Formula | C65H84N10O11 |
|---|---|
| Molecular Weight | 1181.42 |