2538014-94-5
2538014-94-5 structure
- Name: Pemvidutide
- Chemical Name: Pemvidutide
- CAS Number: 2538014-94-5
- Molecular Formula: C182H275N39O54
- Molecular Weight: 3873.35
- Catalog: Research Areas Metabolic Disease
- Create Date: 2023-02-20 10:34:42
- Modify Date: 2026-07-22 16:30:33
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Pemvidutide is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research[1].
| Name | Pemvidutide |
|---|
| Description | Pemvidutide is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research[1]. |
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| Related Catalog | |
| In Vivo | Pemvidutide (subcutaneous injection; 5 or 10 nmol/kg; once daily; 12 w) treatment improves NASH (nonalcoholic steatohepatitis) outcomes in vivo[1]. Animal Model: C57BL6/J mice (with biopsy-confirmed NAS score after 29 weeks on a HFFC diet)[1] Dosage: 5 or 10 nmol/kg Administration: Subcutaneous injection; 5 or 10 nmol/kg; once daily; 12 weeks Result: Lowered hepatic lipids, liver weight, biomarkers of liver injury (plasma ALT and AST), the inflammation marker galactin-3, the fibrosis marker Col1a1, and the NAS score. |
| Molecular Formula | C182H275N39O54 |
|---|---|
| Molecular Weight | 3873.35 |