2819989-68-7
2819989-68-7 structure
- Name: PBRM1-BD2-IN-7
- Chemical Name: PBRM1-BD2-IN-7
- CAS Number: 2819989-68-7
- Molecular Formula: C16H15ClN2O
- Molecular Weight: 286.76
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2022-11-27 11:45:13
- Modify Date: 2024-04-05 17:11:58
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PBRM1-BD2-IN-7 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with an IC50 value of 0.29 μM. PBRM1-BD2-IN-7 can be used for the research of cancer[1].
| Name | PBRM1-BD2-IN-7 |
|---|
| Description | PBRM1-BD2-IN-7 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with an IC50 value of 0.29 μM. PBRM1-BD2-IN-7 can be used for the research of cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 0.29 μM (PBRM1-BD2)[1]. |
| In Vitro | PBRM1-BD2-IN-7 (0, 0.1, 1, and 10 μM; 5 days) selectively inhibit growth of a PBRM1-dependent prostate cancer cell line[1]. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with IC50 value of 0.29 μM[1]. Cell Viability Assay[1] Cell Line: Human prostate cell lines LNCaP, PC3, and RWPE-1 Concentration: 0, 0.1, 1, and 10 μM Incubation Time: 5 days Result: Inhibited LNCaP growth at higher concentrations. |
| Molecular Formula | C16H15ClN2O |
|---|---|
| Molecular Weight | 286.76 |