157862-84-5

157862-84-5 structure

Name: 2-(Pyridin-3-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine
Chemical Name: WAY-639921
CAS Number: 157862-84-5
Molecular Formula: C₁₈H₁₄N₄S
Molecular Weight: 318.40
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2022-11-26 14:22:30
Modify Date: 2024-03-09 20:21:31
PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM). PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease[1].

Name	WAY-639921
Synonyms	4-Quinazolinamine, 2-(3-pyridinyl)-N-(2-thienylmethyl)-

Description	PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM). PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	PDE5
References	[1]. Sarvesh Paliwal, et al. Pharmacophore and molecular docking based identification of novel structurally diverse PDE-5 inhibitors. Medicinal Chemistry Research. 2015, 24, 576-587.

Molecular Formula	C₁₈H₁₄N₄S
Molecular Weight	318.40