1003091-20-0

1003091-20-0 structure

Name: H4R antagonist 3
Chemical Name: WAY-621360-A
CAS Number: 1003091-20-0
Molecular Formula: C₁₉H₂₁ClN₄S
Molecular Weight: 372.91
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2022-11-27 17:32:24
Modify Date: 2025-09-08 10:21:04
H4R antagonist 3 (Example 18) is a histamine-4 receptor antagonist with an EC50 of ＜10 mM. H4R antagonist 3 can be used for the research of prevention of inflammatory, autoimmune, allergic, and ocular diseases[1].

Name	WAY-621360-A
Synonyms	Thieno[2,3-d]pyrimidin-4-amine, 5-(4-chlorophenyl)-N-methyl-N-(1-methyl-4-piperidinyl)-

Description	H4R antagonist 3 (Example 18) is a histamine-4 receptor antagonist with an EC50 of ＜10 mM. H4R antagonist 3 can be used for the research of prevention of inflammatory, autoimmune, allergic, and ocular diseases[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	EC50: ＜10 mM (histamine-4 receptor)[1]
References	[1]. Allen J. Borchardt, et al. Aminopyrimidine inhibitors of histamine receptors for the treatment of disease. Patent US20100063047A1.

Molecular Formula	C₁₉H₂₁ClN₄S
Molecular Weight	372.91