1857340-78-3
1857340-78-3 structure
- Name: 4A3-SC8
- Chemical Name: 4A3-SC8
- CAS Number: 1857340-78-3
- Molecular Formula: C75H139N3O16S4
- Molecular Weight: 1467.2
- Catalog: Research Areas Cancer
- Create Date: 2022-11-21 23:09:04
- Modify Date: 2024-04-11 20:37:24
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4A3-SC8 is a modular degradable dendrimer that enables small RNAs to extend survival in an aggressive liver cancer model[1].
| Name | 4A3-SC8 |
|---|
| Description | 4A3-SC8 is a modular degradable dendrimer that enables small RNAs to extend survival in an aggressive liver cancer model[1]. |
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| Related Catalog | |
| In Vivo | 4A3-SC8 在静脉注射 1mg siRNA/kg 24 小时后介导 siRNA 主要在肝脏中积聚，少量在脾脏和肾脏中积聚，并使小鼠 >95% 的 FVII 被敲低[1]。 4A3-SC8 (100 mg/kg with 4 mg/kg control siRNA siCTR; i.v.; once) 注射后，老鼠生病并在注射后的第一天体重下降了近 20%[1]。 |
| References |
| Molecular Formula | C75H139N3O16S4 |
|---|---|
| Molecular Weight | 1467.2 |