1416067-68-9
1416067-68-9 structure
- Name: Vasomera
- Chemical Name: Vasomera
- CAS Number: 1416067-68-9
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2022-11-21 19:12:18
- Modify Date: 2024-09-17 18:35:01
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Vasomera is a stable long-acting vasoactive intestinal peptide (VIP) agonist. Vasomera acts on the G-protein-coupled VPAC2-receptors. Vasomera can be used for the research of cardiomyopathy associated with dystrophinopathies[1].
| Name | Vasomera |
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| Description | Vasomera is a stable long-acting vasoactive intestinal peptide (VIP) agonist. Vasomera acts on the G-protein-coupled VPAC2-receptors. Vasomera can be used for the research of cardiomyopathy associated with dystrophinopathies[1]. |
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| Related Catalog | |
| In Vivo | Vasomera (i.v.; 7.5 μg/kg/min; single) improves arterial elastance and ventriculo-arterial coupling and improves indices of diastolic function (i.e., lusitropy) in animals with chronic renoprival hypertension mimicking heart failure with preserved ejection fraction (HFpEF)[1]. Animal Model: Rats[1] Dosage: 7.5 μg/kg Administration: IV, 7.5 μg/kg/min, single Result: Decreased the estimated arterial elastance, improved ventriculo-arterial coupling, reduced filling pressures, accelerated the time-constant of relaxation and improved compliance. |
| References |
| No Any Chemical & Physical Properties |