909395-70-6
909395-70-6 structure
- Name: Romosozumab
- Chemical Name: Romosozumab
- CAS Number: 909395-70-6
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Endocrinology
- Create Date: 2022-11-21 23:55:18
- Modify Date: 2024-09-10 18:50:48
-
Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis[1][2].
| Name | Romosozumab |
|---|
| Description | Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Romosozumab (30 mg/kg; s.c. twice a week for 10 weeks) converts trabecular rods into trabecular plates in cynomolgus monkeys[1]. Romosozumab (3 and 30 mg/kg; s.c. once a week for 6 or 12 months) improves bone mass,architecture, and bone strength, and maintains bone quality at the same time in mature cynomolgus monkeys with 4 months post-ovariectomy[2]. Animal Model: Male cynomolgus monkeys[1] Dosage: 30 mg/kg Administration: Subcutaneous injection; 30 mg/kg twice a week for 10 weeks Result: Increased bone formation and plate-like trabecular morphology, and improved mechanical performance. |
| No Any Chemical & Physical Properties |