2839192-35-5

2839192-35-5 structure

Name: Anti-infective agent 6
Chemical Name: Anti-infective agent 6
CAS Number: 2839192-35-5
Molecular Formula: C₁₅H₁₅NO₃
Molecular Weight: 257.28
Catalog: Research Areas Infection
Create Date: 2022-11-16 11:10:05
Modify Date: 2024-04-06 17:44:51
Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM)[1].

Name	Anti-infective agent 6

Description	Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM)[1].
Related Catalog	Research Areas >> Infection
In Vitro	Anti-infective agent 6 (compound 28) is less cytotoxic with a CC50 value higher than 100 μM in macrophage RAW 264.7 cells and consequently a SI higher than 28 for Leishmania parasites[1].
References	[1]. Koumpoura CL, et al. Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides. ACS Omega. 2022 Oct 3;7(40):35635-35655.

Molecular Formula	C₁₅H₁₅NO₃
Molecular Weight	257.28