2226366-86-3
2226366-86-3 structure
- Name: TLR9-IN-1
- Chemical Name: TLR9-IN-1
- CAS Number: 2226366-86-3
- Molecular Formula: C23H31N7O
- Molecular Weight: 421.54
- Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
- Create Date: 2022-10-10 21:00:45
- Modify Date: 2024-04-02 20:12:54
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TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1].
| Name | TLR9-IN-1 |
|---|
| Description | TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1]. |
|---|---|
| Related Catalog | |
| Target |
human TLR9:7 nM (IC50) |
| In Vitro | TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide)[1]. |
| References |
| Molecular Formula | C23H31N7O |
|---|---|
| Molecular Weight | 421.54 |