2411786-32-6
2411786-32-6 structure
- Name: KRAS inhibitor-20
- Chemical Name: KRAS inhibitor-20
- CAS Number: 2411786-32-6
- Molecular Formula: C31H40F4N6O2
- Molecular Weight: 604.68
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-10-22 21:40:39
- Modify Date: 2025-08-22 18:18:30
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KRAS inhibitor-20 is a small molecular inhibitor of KRasG12C, the oncogenic mutant. KRAS inhibitor-20 inhibits KRasG12C with the IC50 value <10 nM[1].
| Name | KRAS inhibitor-20 |
|---|
| Description | KRAS inhibitor-20 is a small molecular inhibitor of KRasG12C, the oncogenic mutant. KRAS inhibitor-20 inhibits KRasG12C with the IC50 value <10 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
KRAS(G12C):<10 nM (IC50, [1]) |
| In Vitro | KRAS inhibitor-20 (compound 12b) results KRasG12C alkylation human lung cancer adenocarcinoma (HCC 1171) with an EC50 value of 3.3 nM[1]. |
| References |
| Molecular Formula | C31H40F4N6O2 |
|---|---|
| Molecular Weight | 604.68 |