192323-14-1
192323-14-1 structure
- Name: hACC2-IN-1
- Chemical Name: hACC2-IN-1
- CAS Number: 192323-14-1
- Molecular Formula: C23H32N2O4S
- Molecular Weight: 432.58
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Acetyl-CoA Carboxylase
- Create Date: 2022-10-07 12:11:15
- Modify Date: 2024-04-07 06:08:49
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hACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2). hACC2-IN-1 could be used for obesity research[1].
| Name | hACC2-IN-1 |
|---|
| Description | hACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2). hACC2-IN-1 could be used for obesity research[1]. |
|---|---|
| Related Catalog | |
| Target |
hACC2:2.5 μM (IC50) |
| In Vitro | ACC2 isoform, presents on the mitochondrial surface, inhibits carnitine palmitoyl transferase 1 (CPT-1) and converts acetyl-CoA into malonylCoA for de novo lipogenesis in the cytosol[1]. ACCs inhibition will change cellular substrate and favour lipid oxidation, thus preventing deleterious lipids from accumulating in oxidative tissue such as muscle, heart and liver[1]. hACC2-IN-1 shows good potency against the human ACC2 (hACC2) enzyme[1]. |
| References |
| Molecular Formula | C23H32N2O4S |
|---|---|
| Molecular Weight | 432.58 |