Name | Dasiglucagon |
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Description | Dasiglucagon is a novel human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research[1][2][3]. |
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Related Catalog | |
In Vivo | 1.19Dasiglucagon PK profile shows a dose-dependent and rapid increase in plasma levels[2]. Dasiglucagon dose 0.1 mg 0.3 mg 0.6 mg 1.0 mg N 5 16 16 16 AUC0–30min (pmol*h/L) 99.4 (32.0) 302 (78.9) 444 (163) 884 (307) AUC0–360min (pmol*h/L) 451 (123) 1360 (166) 1630 (368) 4800 (697) AUC0–inf (pmol*h/L) 451 (123) 1360 (166) 2640 (365) 4810 (696) Cmax (pmol/L) 334 (113) 976 (208) 1570 (445) 2800 (767) tmax (h) 0.50 (0.5-0.6) 0.63 (0.3-0.8) 0.58 (0.5-1.7) 0.63 (0.3-0.8) t1/2 (h) 0.43 (0.07) 0.43 (0.07) 0.49 (0.14) 0.54 (0.17) |
References |
Molecular Formula | C152H222N38O50 |
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Molecular Weight | 3381.62 |