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62497-68-1

62497-68-1 structure

62497-68-1 structure

Name: Clonidine-d4
Chemical Name: Clonidine-d4
CAS Number: 62497-68-1
Molecular Formula: C₉H₅D₄Cl₂N₃
Molecular Weight: 234.12
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2022-11-21 18:41:22
Modify Date: 2024-01-09 09:34:20
Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent[1][2][3][4][5].

Name	Clonidine-d4

Description	Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent[1][2][3][4][5].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19(1):9-15.;Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expres

Molecular Formula	C₉H₅D₄Cl₂N₃
Molecular Weight	234.12