945490-09-5

945490-09-5 structure

945490-09-5 structure

Name: Tomaymycin DM
Chemical Name: Tomaymycin DM
CAS Number: 945490-09-5
Molecular Formula: C₁₄H₁₄N₂O₃
Molecular Weight: 258.27
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2022-09-18 11:10:59
Modify Date: 2024-01-22 14:41:40
Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).

Name	Tomaymycin DM

Description	Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Target	Pyrrolobenzodiazepines
References	[1]. Dr. Julia Mantaj, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody–Drug Conjugates (ADCs). Angew Chem Int Ed Engl. 2017 Jan 9; 56(2): 462–488.

Molecular Formula	C₁₄H₁₄N₂O₃
Molecular Weight	258.27