2409178-86-3

2409178-86-3 structure
2409178-86-3 structure
  • Name: SARS 3CLpro-IN-1
  • Chemical Name: SARS 3CLpro-IN-1
  • CAS Number: 2409178-86-3
  • Molecular Formula: C22H38N4O2
  • Molecular Weight: 390.56
  • Catalog: Signaling Pathways Anti-infection SARS-CoV
  • Create Date: 2022-09-10 14:29:19
  • Modify Date: 2025-12-01 19:08:10
  • SARS 3CLpro-IN-1 (Compound 3b) is a SARS 3CL protease inhibitor with an IC50 value of 95 μM, as a specific stereo isomerof the octahydroisochromene scaffold, directs the P1 site imidazole[1].

Name SARS 3CLpro-IN-1
Description SARS 3CLpro-IN-1 (Compound 3b) is a SARS 3CL protease inhibitor with an IC50 value of 95 μM, as a specific stereo isomerof the octahydroisochromene scaffold, directs the P1 site imidazole[1].
Related Catalog
Target

IC50: 95 μM (SARS 3CL protease) [1]

In Vitro SARS 3CLpro-IN-1 (Compound 3b) has high active (IC50=95 μM) and had a (1S, 3S)-configuration in the ring system[1].
References

[1]. Shin-Ichiro Yoshizawa, et al. Evaluation of an octahydroisochromene scaffold used as a novel SARS 3CL protease inhibitor. Bioorg Med Chem. 2020 Feb 15;28(4):115273.

Molecular Formula C22H38N4O2
Molecular Weight 390.56
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