1357950-47-0

1357950-47-0 structure

Name: Plasma kallikrein-IN-3
Chemical Name: Plasma kallikrein-IN-3
CAS Number: 1357950-47-0
Molecular Formula: C₂₀H₂₃N₅O₂
Molecular Weight: 365.43
Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
Create Date: 2022-09-19 17:25:23
Modify Date: 2024-04-05 18:20:21
Plasma kallikrein-IN-3 is a plasma kallikrein inhibitor (IC50: 0.15 μM). Plasma kallikrein-IN-3 can be used for hereditary angioedema, diabetic macular edema, and diabetic retinopathy research[1].

Name	Plasma kallikrein-IN-3

Description	Plasma kallikrein-IN-3 is a plasma kallikrein inhibitor (IC50: 0.15 μM). Plasma kallikrein-IN-3 can be used for hereditary angioedema, diabetic macular edema, and diabetic retinopathy research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cardiovascular Disease Research Areas >> Metabolic Disease
Target	Plasma kallikrein[1]
In Vitro	Plasma kallikrein-IN-3 (example 13, 1 nM-100 μM, 1 h) inhibits plasma kallikrein activity with an IC<>50 value of 0.15 μM[1].
References	[1]. Brandl Trixi, et al. Preparation of N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides as inhibitors of plasma kallikrein. Patent WO2012017020.

Molecular Formula	C₂₀H₂₃N₅O₂
Molecular Weight	365.43