2451573-87-6
2451573-87-6 structure
- Name: dTAGV-1-NEG
- Chemical Name: dTAGV-1-NEG
- CAS Number: 2451573-87-6
- Molecular Formula: C68H90N6O14S
- Molecular Weight: 1247.54
- Catalog: Research Areas Cancer
- Create Date: 2022-09-08 20:14:18
- Modify Date: 2025-05-20 18:01:03
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dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader[1].
| Name | dTAGV-1-NEG |
|---|
| Description | dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader[1]. |
|---|---|
| Related Catalog | |
| In Vitro | dTAGV-1-NEG (1-10 µM; 24 h) not induces the degradation of FKBP12F36V-Nluc on 293FT FKBP12F36V-Nluc or FKBP12WT-Nluc cells[1]. dTAGV-1-NEG (500 nM; 24 h) dose not induce the degradation of KRASG12V protein in PATU-8902 FKBP12F36V-KRASG12V and KRAS−/− cells[1]. Western Blot Analysis[1] Cell Line: PATU-8902 FKBP12F36V-KRASG12V, KRAS−/− cells Concentration: 500 nM Incubation Time: 1-24 h Result: Not induced the degradation of KRASG12V protein. |
| References |
| Molecular Formula | C68H90N6O14S |
|---|---|
| Molecular Weight | 1247.54 |