1870849-34-5

1870849-34-5 structure

Name: Bromodomain inhibitor-9
Chemical Name: Bromodomain inhibitor-9
CAS Number: 1870849-34-5
Molecular Formula: C₂₄H₂₈N₄O₅S
Molecular Weight: 484.57
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2022-09-01 06:14:09
Modify Date: 2024-01-17 07:42:15
Bromodomain inhibitor-9 is a Bromodomains inhibitor that selectively inhibits BRD4-1 (Kd: 12 nM). Bromodomain inhibitor-9 can be used in the research of diseases or conditions associated with systemic or tissue inflammation, lipid metabolism, fibrosis or chronic autoimmune diseases[1].

Name	Bromodomain inhibitor-9

Description	Bromodomain inhibitor-9 is a Bromodomains inhibitor that selectively inhibits BRD4-1 (Kd: 12 nM). Bromodomain inhibitor-9 can be used in the research of diseases or conditions associated with systemic or tissue inflammation, lipid metabolism, fibrosis or chronic autoimmune diseases[1].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4-1:12 nM (Kd) BRD4-2:5600 nM (Kd)
In Vitro	Bromodomain inhibitor-9 (Compound 99, 1 h) inhibits LPS induced cytokines (IL12P40) release in PBMCs, with an IC50 value of 400 nM[1].
References	[1]. Gerner Seitzberg, et al. Heterocyclic compounds as inhibitors of bromodomains and their preparation. Patent WO2016016316.

Molecular Formula	C₂₄H₂₈N₄O₅S
Molecular Weight	484.57