2446063-14-3

2446063-14-3 structure

Name: α-Amylase/α-Glucosidase-IN-2
Chemical Name: α-Amylase/α-Glucosidase-IN-2
CAS Number: 2446063-14-3
Molecular Formula: C₂₂H₁₆ClN₅
Molecular Weight: 385.85
Catalog: Research Areas Metabolic Disease
Create Date: 2022-08-16 16:32:56
Modify Date: 2024-01-13 23:08:32
α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1].

Name	α-Amylase/α-Glucosidase-IN-2

Description	α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	IC50: 13.02 µM (α-amylase); 13.09 µM (α-glucosidase)[1].
References	[1]. Shamim S, et al. Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase. Bioorg Chem. 2020 Aug;101:103979.

Molecular Formula	C₂₂H₁₆ClN₅
Molecular Weight	385.85