2439096-14-5

2439096-14-5 structure

2439096-14-5 structure

Name: VEGFR-2-IN-27
Chemical Name: VEGFR-2-IN-27
CAS Number: 2439096-14-5
Molecular Formula: C₂₅H₂₁FN₄O₄
Molecular Weight: 460.46
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2022-08-30 11:08:54
Modify Date: 2024-01-16 09:31:24
VEGFR-2-IN-27 (compound 7a) is a highly potent VEGFR-2 inhibitor with an IC50 value of 14.8 nM. VEGFR-2-IN-27 can be used for researching anticancer[1].

Name	VEGFR-2-IN-27

Description	VEGFR-2-IN-27 (compound 7a) is a highly potent VEGFR-2 inhibitor with an IC50 value of 14.8 nM. VEGFR-2-IN-27 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR-2:14.8 nM (IC50)
References	[1]. Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961.

Molecular Formula	C₂₅H₂₁FN₄O₄
Molecular Weight	460.46