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519021-48-8

519021-48-8 structure

519021-48-8 structure

Name: pUL89 Endonuclease-IN-2
Chemical Name: pUL89 Endonuclease-IN-2
CAS Number: 519021-48-8
Molecular Formula: C₁₇H₁₂F₃N₃O₃S
Molecular Weight: 395.36
Catalog: Signaling Pathways Anti-infection CMV
Create Date: 2022-08-05 10:34:49
Modify Date: 2025-08-27 18:45:59
pUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 of 3.0 μM. Antiviral activities[1].

Name	pUL89 Endonuclease-IN-2

Description	pUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 of 3.0 μM. Antiviral activities[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> CMV
In Vitro	Cell Viability Assay Cell Line: HFF cells Concentration: 10 μM Incubation Time: 168 hours Result: Inhibited HCMV replication in HFF cell with the EC50 value of 14.4 μM.
References	[1]. Tianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849.

Molecular Formula	C₁₇H₁₂F₃N₃O₃S
Molecular Weight	395.36

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