1296818-77-3

1296818-77-3 structure
1296818-77-3 structure
  • Name: Nesvacumab
  • Chemical Name: Nesvacumab
  • CAS Number: 1296818-77-3
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2022-08-17 12:55:27
  • Modify Date: 2024-01-14 02:10:38
  • Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1[1].

Name Nesvacumab
Description Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1[1].
Related Catalog
References

[1]. Kyriakos P Papadopoulos, et al. A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Mar 15;22(6):1348-55.

No Any Chemical & Physical Properties
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