2522596-01-4

2522596-01-4 structure

Name: Kurzipene D
Chemical Name: Kurzipene D
CAS Number: 2522596-01-4
Molecular Formula: C₂₆H₃₆O₈
Molecular Weight: 476.56
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-17 11:06:48
Modify Date: 2024-01-02 20:04:35
Kurzipene D (compound 4) is a potent anticancer agent. Kurzipene D induces the apoptosis and arrested the HepG2 cell cycle at S stage. Kurzipene D shows anti-tumor effects using in vivo zebrafish model. Kurzipene D has the property of inhibiting tumor proliferation and migration[1].

Name	Kurzipene D

Description	Kurzipene D (compound 4) is a potent anticancer agent. Kurzipene D induces the apoptosis and arrested the HepG2 cell cycle at S stage. Kurzipene D shows anti-tumor effects using in vivo zebrafish model. Kurzipene D has the property of inhibiting tumor proliferation and migration[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Kurzipene D (compound 4) shows strong cytotoxic activity against cancer cells K562, HepG2, A549, and HeLa, with IC50 values of 7.2 ± 0.4, 9.7 ± 0.3, 10.9 ± 0.6, and 12.4 ± 1.0, respectively[1].
References	[1]. Liang Y, et al. Diterpenoids from the leaves of Casearia kurzii showing cytotoxic activities. Bioorg Chem. 2020 May;98:103741.

Molecular Formula	C₂₆H₃₆O₈
Molecular Weight	476.56