848249-35-4

848249-35-4 structure

Name: 2-(2-Ethylphenoxy)-N-(2-methyl-4-(pyrrolidin-1-yl)phenyl)acetamide
Chemical Name: JAMM protein inhibitor 2
CAS Number: 848249-35-4
Molecular Formula: C₂₁H₂₆N₂O₂
Molecular Weight: 338.44
Catalog: Research Areas Cancer
Create Date: 2022-08-24 20:38:32
Modify Date: 2025-11-02 18:38:00
JAMM protein inhibitor 2 (compound 180) is a potent JAMM protease inhibitor with IC50s of 10 μM, 46 μM and 89 μM for thrombin, Rpn11 and MMP2, respectively. JAMM protein inhibitor 2 can be used for researching anticancer[1]

Name	JAMM protein inhibitor 2

Description	JAMM protein inhibitor 2 (compound 180) is a potent JAMM protease inhibitor with IC50s of 10 μM, 46 μM and 89 μM for thrombin, Rpn11 and MMP2, respectively. JAMM protein inhibitor 2 can be used for researching anticancer[1]
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	:IC50: 10 μM (thrombin), 46 μM (Rpn11), 89 μM (MMP2)[1]
References	[1]. Han-Jie Zhou, et al. Methods and compositions for jamm protease inhibition. WO2013123071A1 (compound 180)

Molecular Formula	C₂₁H₂₆N₂O₂
Molecular Weight	338.44