2756016-53-0

2756016-53-0 structure
2756016-53-0 structure
  • Name: Heterophdoid A
  • Chemical Name: Heterophdoid A
  • CAS Number: 2756016-53-0
  • Molecular Formula: C26H42O10
  • Molecular Weight: 514.61
  • Catalog: Signaling Pathways Immunology/Inflammation COX
  • Create Date: 2022-08-16 11:38:29
  • Modify Date: 2024-01-09 16:32:02
  • Heterophdoid A (Compound 1) is an anti-inflammatory agent. Heterophdoid A inhibits NO production with an IC50 of 5.93 μM in BV-2 cells[1].

Name Heterophdoid A
Description Heterophdoid A (Compound 1) is an anti-inflammatory agent. Heterophdoid A inhibits NO production with an IC50 of 5.93 μM in BV-2 cells[1].
Related Catalog
Target

NO production:5.93 μM (IC50)

COX-2

In Vitro Heterophdoid A (Compound 1) (0-10 μM) decreases the expression of iNOS and COX-2[1].
In Vivo Heterophdoid A (Compound 1) (0-10 μM) suppresses ROS and NO dose-dependently in a zebrafish model[1].
References

[1]. Wu P, et al. Natural iridoids from Patrinia heterophylla showing anti-inflammatory activities in vitro and in vivo. Bioorg Chem. 2020 Nov;104:104331.

Molecular Formula C26H42O10
Molecular Weight 514.61
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