Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FSG67
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: FSG67
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1158383-34-6

1158383-34-6 structure

1158383-34-6 structure

Name: FSG67
Chemical Name: FSG67
CAS Number: 1158383-34-6
Molecular Formula: C₁₆H₂₅NO₄S
Molecular Weight: 327.44
Catalog: Research Areas Metabolic Disease
Create Date: 2022-08-11 22:54:46
Modify Date: 2024-01-13 15:32:36
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM[1].

Name	FSG67

Description	FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	GPAT[1]
In Vitro	FSG67 reduces GSK3β phosphorylation and signaling after acetaminophen overdose[1]. FSG67 results in a dose-dependent increase in oxidative metabolism in mature adipocytes with an IC50 of 27.7 ± 4.4 μM[2].
References	[1]. Clemens MM, et al. The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling. Food Chem Toxicol. 2019 Mar;125:279-288. [2]. Reilly SM, et al. Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nat Metab. 2020 Jul;2(7):620-634.

Molecular Formula	C₁₆H₂₅NO₄S
Molecular Weight	327.44

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