101143-87-7

101143-87-7 structure

Name: Ep vinyl quinidine
Chemical Name: Ep vinyl quinidine
CAS Number: 101143-87-7
Molecular Formula: C₂₀H₂₄N₂O₂
Molecular Weight: 324.42
Catalog: Research Areas Cardiovascular Disease
Create Date: 2022-08-18 18:01:42
Modify Date: 2024-09-22 18:53:46
Ep vinyl quinidine (3-Epiquinine) is an epi-vinyl stereoisomer of Quinidine. Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine can be used for malaria research[1][2][3].

Name	Ep vinyl quinidine

Description	Ep vinyl quinidine (3-Epiquinine) is an epi-vinyl stereoisomer of Quinidine. Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine can be used for malaria research[1][2][3].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Infection
Target	Parasite[1]
References	[1]. Hu B, et al. Origin of and a Solution for Uneven Efficiency by Cinchona Alkaloid-Derived, Pseudoenantiomeric Catalysts for Asymmetric Reactions. J Am Chem Soc. 2018 Oct 24;140(42):13913-13920. [2]. Kehl SJ. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13. [3]. Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide. Pharmacol Ther. 1983;23(2):179-91.

Molecular Formula	C₂₀H₂₄N₂O₂
Molecular Weight	324.42