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1774353-12-6

1774353-12-6 structure
1774353-12-6 structure
  • Name: 6bK
  • Chemical Name: 6bK
  • CAS Number: 1774353-12-6
  • Molecular Formula: C43H56F3N7O9
  • Molecular Weight: 871.94
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2022-08-17 23:31:13
  • Modify Date: 2025-08-22 09:30:46
  • 6bK is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. 6bK increases circulating insulin in high-fat-fed mice. Acute administration of 6bK enhances glucose tolerance to oral glucose, notably to a greater extent in high-fat-fed mice[1].

Name 6bK
Description 6bK is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. 6bK increases circulating insulin in high-fat-fed mice. Acute administration of 6bK enhances glucose tolerance to oral glucose, notably to a greater extent in high-fat-fed mice[1].
Related Catalog
Target

IC50: 50 nM (IDE)[1]

References

[1]. Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell Metab. 2014;20(2):201-203.

Molecular Formula C43H56F3N7O9
Molecular Weight 871.94
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