325775-42-6

325775-42-6 structure

Name: NAAA-IN-2
Chemical Name: NAAA-IN-2
CAS Number: 325775-42-6
Molecular Formula: C₁₁H₁₃N₃O₂S
Molecular Weight: 251.30
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-07-01 18:09:00
Modify Date: 2025-08-25 12:04:13
NAAA-IN-2 (Compound 9) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-2 has the potential for the research of inflammation and pain[1].

Name	NAAA-IN-2

Description	NAAA-IN-2 (Compound 9) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-2 has the potential for the research of inflammation and pain[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195.

Molecular Formula	C₁₁H₁₃N₃O₂S
Molecular Weight	251.30