2404603-41-2

2404603-41-2 structure

2404603-41-2 structure

Name: ITK inhibitor 5
Chemical Name: ITK inhibitor 5
CAS Number: 2404603-41-2
Molecular Formula: C₂₁H₁₈F₂N₄O₂
Molecular Weight: 396.39
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Itk
Create Date: 2022-06-26 15:42:38
Modify Date: 2024-01-06 22:38:00
ITK inhibitor 5 (compound 27) is a potent and selective ITK inhibitor with IC50s of 5.6, 25 nM for ITK, BTK, respectively[1].

Name	ITK inhibitor 5

Description	ITK inhibitor 5 (compound 27) is a potent and selective ITK inhibitor with IC50s of 5.6, 25 nM for ITK, BTK, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Itk
References	[1]. Wang X, et al. Design, synthesis and structure-activity relationship of indolylindazoles as potent and selective covalent inhibitors of interleukin-2 inducible T-cell kinase (ITK). Eur J Med Chem. 2020 Feb 1;187:111918.

Molecular Formula	C₂₁H₁₈F₂N₄O₂
Molecular Weight	396.39