2302046-54-2

2302046-54-2 structure

Name: HIV-1 inhibitor-27
Chemical Name: HIV-1 inhibitor-27
CAS Number: 2302046-54-2
Molecular Formula: C₄₆H₇₈N₂O₇
Molecular Weight: 771.12
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-07-01 12:01:25
Modify Date: 2024-01-10 20:29:00
HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS[1].

Name	HIV-1 inhibitor-27

Description	HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	HIV-1 YU2:16 μM (IC50) HIV-1 NL4-3:0.5 μM (IC50) HIV-1 89.6:0.39 μM (IC50)
References	[1]. Takeuchi R, et al. Design, synthesis, and bio-evaluation of novel triterpenoid derivatives as anti-HIV-1 compounds. Bioorg Med Chem Lett. 2022;69:128768.

Molecular Formula	C₄₆H₇₈N₂O₇
Molecular Weight	771.12