1627094-88-5

1627094-88-5 structure

1627094-88-5 structure

Name: Gü2602
Chemical Name: Gü2602
CAS Number: 1627094-88-5
Molecular Formula: C₁₆H₂₂N₄O₃
Molecular Weight: 318.37
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cathepsin
Create Date: 2022-06-27 12:09:51
Modify Date: 2024-01-09 18:52:49
Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].

Name	Gü2602

Description	Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Ki: 0.013 nM (mCatK)[1]
References	[1]. Benýšek J, et al. Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem. 2022 Dec;37(1):515-526.

Molecular Formula	C₁₆H₂₂N₄O₃
Molecular Weight	318.37