2423992-63-4

2423992-63-4 structure

Name: FGFR4-IN-12
Chemical Name: FGFR4-IN-12
CAS Number: 2423992-63-4
Molecular Formula: C₃₄H₃₂Cl₂N₄O₆
Molecular Weight: 663.55
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
Create Date: 2022-07-01 17:12:36
Modify Date: 2025-08-27 11:49:23
FGFR4-IN-12 (Compound A34) is a potent inhibitor of FGFR4. FGFR4-IN-12 exhibits improved FGFR4 inhibitory capability and selectivity and excellent anti-proliferative activities against FGFR4-dependent HCC cell lines. FGFR4-IN-12 has the potential for the research of cancer diseases[1].

Name	FGFR4-IN-12

Description	FGFR4-IN-12 (Compound A34) is a potent inhibitor of FGFR4. FGFR4-IN-12 exhibits improved FGFR4 inhibitory capability and selectivity and excellent anti-proliferative activities against FGFR4-dependent HCC cell lines. FGFR4-IN-12 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
References	[1]. Zhang X, et al. Discovery of 1,6-Naphthyridin-2(1H)-one Derivatives as Novel, Potent, and Selective FGFR4 Inhibitors for the Treatment of Hepatocellular Carcinoma. J Med Chem. 2022;65(11):7595-7618.

Molecular Formula	C₃₄H₃₂Cl₂N₄O₆
Molecular Weight	663.55