2479918-59-5
2479918-59-5 structure
- Name: CAXII-IN-1
- Chemical Name: CAXII-IN-1
- CAS Number: 2479918-59-5
- Molecular Formula: C13H7Cl2NO3S
- Molecular Weight: 328.17
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
- Create Date: 2022-06-26 16:22:23
- Modify Date: 2024-01-06 17:12:20
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CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with Ki values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity[1].
| Name | CAXII-IN-1 |
|---|
| Description | CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with Ki values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 3.8 nM (hCA XII), 56.0 nM (hCA IX)[1] |
| In Vitro | CAXII-IN-1 (Compound 17) shows cytotoxicity with IC50 values of 20±1, 4.8±0.03 and 14±2 µM against MCF-7, HeLa and A549 cells, respectively[1]. |
| References |
| Molecular Formula | C13H7Cl2NO3S |
|---|---|
| Molecular Weight | 328.17 |