Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ARUK3001185
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ARUK3001185
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2411969-39-4

2411969-39-4 structure

2411969-39-4 structure

Name: ARUK3001185
Chemical Name: ARUK3001185
CAS Number: 2411969-39-4
Molecular Formula: C₉H₄Cl₂F₃N₃
Molecular Weight: 282.05
Catalog: Signaling Pathways Stem Cell/Wnt Wnt
Create Date: 2022-07-01 06:45:52
Modify Date: 2025-08-25 21:29:00
ARUK3001185 (Compound 8l) is a potent, selective, orally active and brain-penetrant inhibitor of Notum activity with an IC50 of 6.7 nM[1].

Name	ARUK3001185

Description	ARUK3001185 (Compound 8l) is a potent, selective, orally active and brain-penetrant inhibitor of Notum activity with an IC50 of 6.7 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt
Target	IC50: 6.7 nM (Notum)[1]
References	[1]. Willis NJ, et al. Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J Med Chem. 2022 May 26;65(10):7212-7230.

Molecular Formula	C₉H₄Cl₂F₃N₃
Molecular Weight	282.05

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