2388983-64-8

2388983-64-8 structure

Name: Anticancer agent 52
Chemical Name: Anticancer agent 52
CAS Number: 2388983-64-8
Molecular Formula: C₅₀H₄₃Br₂N₂P
Molecular Weight: 862.67
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-07-11 22:24:25
Modify Date: 2024-01-14 10:42:52
Anticancer agent 52 is a potent anticancer agent. Anticancer agent 52 shows in vitro cytotoxicity. Anticancer agent 52 induces apoptosis. Anticancer agent 52 shows antitumor effect. Anticancer agent 52 has the potential for the research of bladder cancer[1].

Name	Anticancer agent 52

Description	Anticancer agent 52 is a potent anticancer agent. Anticancer agent 52 shows in vitro cytotoxicity. Anticancer agent 52 induces apoptosis. Anticancer agent 52 shows antitumor effect. Anticancer agent 52 has the potential for the research of bladder cancer[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Anticancer agent 52 (compound TPP1) (0-2048 µM) shows cytotoxicity with IC50s of 200, 200, 150, 200, 240, 80 µM for 5637, RT112, RT4, SWT80, TCCSUP, UMUC3 cells, respectively[1]. Apoptosis Analysis[1] Cell Line: RT112 cells Concentration: 200 µM Incubation Time: 1, 2, 4 h Result: Induced apoptosis with the increased the expression of c-PARP.
References	[1]. Stromyer ML, et al. Synthesis, characterization, and biological activity of a triphenylphosphonium-containing imidazolium salt against select bladder cancer cell lines. Eur J Med Chem. 2020 Jan 1;185:111832.

Molecular Formula	C₅₀H₄₃Br₂N₂P
Molecular Weight	862.67