423128-55-6

423128-55-6 structure

Name: RUVBL1/2 ATPase-IN-1
Chemical Name: RUVBL1/2 ATPase-IN-1
CAS Number: 423128-55-6
Molecular Formula: C₂₈H₂₈F₃N₅O
Molecular Weight: 507.55
Catalog: Research Areas Cancer
Create Date: 2022-07-08 08:35:36
Modify Date: 2024-01-07 17:09:15
RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1].

Name	RUVBL1/2 ATPase-IN-1

Description	RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726.

Molecular Formula	C₂₈H₂₈F₃N₅O
Molecular Weight	507.55