2714484-71-4

2714484-71-4 structure

2714484-71-4 structure

Name: Metolazone-d7
Chemical Name: Metolazone-d7
CAS Number: 2714484-71-4
Molecular Formula: C₁₆H₉D₇ClN₃O₃S
Molecular Weight: 372.88
Catalog: Signaling Pathways Metabolic Enzyme/Protease Thrombin
Create Date: 2022-07-01 21:47:18
Modify Date: 2024-01-05 22:39:14
Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

Name	Metolazone-d7

Description	Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Stern A. Metolazone, a diuretic agent. Am Heart J. 1976 Feb;91(2):262-3. [3]. Thompson DM. A new antihypertensive: metolazone treatment of hypertension. J Kans Med Soc. 1977 Jul;78(7):337-9, 342.

Molecular Formula	C₁₆H₉D₇ClN₃O₃S
Molecular Weight	372.88