1192354-74-7

1192354-74-7 structure
1192354-74-7 structure
  • Name: Estradiol benzoate-d3
  • Chemical Name: Estradiol benzoate-d3
  • CAS Number: 1192354-74-7
  • Molecular Formula: C25H25D3O3
  • Molecular Weight: 379.51
  • Catalog: Signaling Pathways Others Estrogen Receptor/ERR
  • Create Date: 2022-07-01 16:43:41
  • Modify Date: 2024-01-08 14:19:44
  • Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

Name Estradiol benzoate-d3
Description Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Zovko M, et al. Macromolecular prodrugs XI. Synthesis and characterization of polymer-estradiol conjugate. Int J Pharm. 2004 Nov 5;285(1-2):35-41.

[3]. García-Gómez E, et al. Role of sex steroid hormones in bacterial-host interactions. Biomed Res Int. 2013;2013:928290.

[4]. Estradiol benzoate

Molecular Formula C25H25D3O3
Molecular Weight 379.51