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2597167-22-9

2597167-22-9 structure
2597167-22-9 structure
  • Name: Azido-PEG2-VHL
  • Chemical Name: Azido-PEG2-VHL
  • CAS Number: 2597167-22-9
  • Molecular Formula: C29H41N7O6S
  • Molecular Weight: 615.74
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2022-09-01 13:16:16
  • Modify Date: 2024-03-01 13:47:55
  • Azido-PEG2-VHL is a multikinase degrader which can be used in the synthesis of PROTACs[1].

Name Azido-PEG2-VHL
Description Azido-PEG2-VHL is a multikinase degrader which can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References

[1]. STATSYUK A, et, al. Multikinase degraders. WO2021021797A1.

[2]. Chung CW, et, al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.

Molecular Formula C29H41N7O6S
Molecular Weight 615.74