1902910-89-7
1902910-89-7 structure
- Name: AC-386
- Chemical Name: AC-386
- CAS Number: 1902910-89-7
- Molecular Formula: C35H34FN5O6
- Molecular Weight: 639.67
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK c-Met/HGFR
- Create Date: 2022-06-24 18:08:34
- Modify Date: 2025-08-27 14:02:26
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AC-386 is a highly potent c-Met inhibitor with IC50 value of 7.42 nM. AC-386 has antiproliferative activities against certain cancer cell lines. AC-386 can be used for researching anti-cancer resistance[1].
| Name | AC-386 |
|---|
| Description | AC-386 is a highly potent c-Met inhibitor with IC50 value of 7.42 nM. AC-386 has antiproliferative activities against certain cancer cell lines. AC-386 can be used for researching anti-cancer resistance[1]. |
|---|---|
| Related Catalog | |
| Target |
c-Met:7.42 nM (IC50) |
| In Vitro | AC-386 (0-20 μM; 72 hours) exhibits antiproliferative activities against HCT-116, MCF-7 and A549[1]. Cell Proliferation Assay Cell Line: HCT-116, MCF-7 and A549[1] Concentration: 0-20 μM Incubation Time: 72 hours Result: Exhibited antiproliferative activities against HCT-116, MCF-7 and A549 with IC50s of 0.37 ± 0.02 μM, 0.63 ± 0.05 μM, 1.12 ± 0.10 μM in HCT-116, MCF-7 and A549, respectively. |
| References |
| Molecular Formula | C35H34FN5O6 |
|---|---|
| Molecular Weight | 639.67 |