2699603-89-7

2699603-89-7 structure

Name: HPK1-IN-28
Chemical Name: HPK1-IN-28
CAS Number: 2699603-89-7
Molecular Formula: C₂₅H₂₂F₃N₅O₄
Molecular Weight: 513.47
Catalog: Signaling Pathways MAPK/ERK Pathway MAP4K
Create Date: 2022-05-25 16:44:05
Modify Date: 2025-09-26 09:29:22
HPK1-IN-28 is a potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-28 enhances the body's anti-tumor immunity. HPK1-IN-28 has the potential for the research of immune-related diseases, especially tumor (extracted from patent WO2021175270A1, compound 1)[1].

Name	HPK1-IN-28

Description	HPK1-IN-28 is a potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-28 enhances the body's anti-tumor immunity. HPK1-IN-28 has the potential for the research of immune-related diseases, especially tumor (extracted from patent WO2021175270A1, compound 1)[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAP4K Research Areas >> Cancer
References	[1]. Jiang Lei, et al. Novel hpk1 inhibitors and methods of preparation and application thereof. Patent WO2021175270A1.

Molecular Formula	C₂₅H₂₂F₃N₅O₄
Molecular Weight	513.47