2728752-20-1
2728752-20-1 structure
- Name: Bcl-2-IN-5
- Chemical Name: Bcl-2-IN-5
- CAS Number: 2728752-20-1
- Molecular Formula: C55H63FN8O8S
- Molecular Weight: 1015.20
- Catalog: Signaling Pathways Apoptosis Bcl-2 Family
- Create Date: 2022-07-04 18:58:06
- Modify Date: 2024-04-03 07:37:32
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Bcl-2-IN-5 is a BCL-2 inhibitor with IC50s of 0.12 nM, 0.14 nM and 0.22 nM for Bcl-2 wild type, Bcl-2 D103Y and Bcl-2 G101V, respectively. Bcl-2-IN-5 inhibits the cell growth with IC50 values of 0.2 nM and 0.44 nM for Bcl 2-G101V knock-in RS4; 11 and RS4; 11 cells, respectively (WO2021208963A1; Example 155)[1].
| Name | Bcl-2-IN-5 |
|---|
| Description | Bcl-2-IN-5 is a BCL-2 inhibitor with IC50s of 0.12 nM, 0.14 nM and 0.22 nM for Bcl-2 wild type, Bcl-2 D103Y and Bcl-2 G101V, respectively. Bcl-2-IN-5 inhibits the cell growth with IC50 values of 0.2 nM and 0.44 nM for Bcl 2-G101V knock-in RS4; 11 and RS4; 11 cells, respectively (WO2021208963A1; Example 155)[1]. |
|---|---|
| Related Catalog | |
| Target |
Bcl-2:0.12 nM (IC50) Bcl-2 D103Y:0.14 nM (IC50) Bcl-2 G101V:0.22 nM (IC50) |
| References |
| Molecular Formula | C55H63FN8O8S |
|---|---|
| Molecular Weight | 1015.20 |