1623143-67-8

1623143-67-8 structure

Name: AP5 sodium
Chemical Name: AP5 sodium
CAS Number: 1623143-67-8
Molecular Formula: C₂₈H₂₇FNNaO₄
Molecular Weight: 483.51
Catalog: Signaling Pathways GPCR/G Protein GPR40
Create Date: 2022-05-21 13:19:26
Modify Date: 2024-01-18 21:59:01
AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research[1].

Name	AP5 sodium

Description	AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR40 Research Areas >> Metabolic Disease
References	[1]. Chen HY, et al. Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs. ACS Med Chem Lett. 2018 Jun 14;9(7):685-690.

Molecular Formula	C₂₈H₂₇FNNaO₄
Molecular Weight	483.51