2252262-24-9

2252262-24-9 structure
2252262-24-9 structure
  • Name: Sabatolimab
  • Chemical Name: Sabatolimab
  • CAS Number: 2252262-24-9
  • Molecular Formula:
  • Molecular Weight:
  • Create Date: 2022-07-12 16:08:16
  • Modify Date: 2024-01-10 20:50:22
  • Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells[1].

Name Sabatolimab
Description Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells[1].
Related Catalog
References

[1]. Andrew M. Brunner, et al. Efficacy and Safety of Sabatolimab (MBG453) in Combination with Hypomethylating Agents (HMAs) in Patients with Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (HR-MDS): Updated Results from a Phase 1b Study. Blood (2020) 136 (Supplement 1): 1–2.

No Any Chemical & Physical Properties