2417987-45-0
2417987-45-0 structure
- Name: GDC-6036
- Chemical Name: GDC-6036
- CAS Number: 2417987-45-0
- Molecular Formula: C29H32ClF4N7O2
- Molecular Weight: 622.06
- Create Date: 2022-05-17 12:29:20
- Modify Date: 2025-08-27 08:39:37
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GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1].
| Name | GDC-6036 |
|---|
| Description | GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1]. |
|---|---|
| Related Catalog | |
| Target |
K-Ras(G12C):<0.01 μM (IC50) |
| References |
[1]. Sushant Malhotra, et al. Fused ring compounds. WO2020097537A2. |
| Molecular Formula | C29H32ClF4N7O2 |
|---|---|
| Molecular Weight | 622.06 |