891861-48-6

891861-48-6 structure

Name: CKLF1-C27
Chemical Name: CKLF1-C27
CAS Number: 891861-48-6
Molecular Formula: C₁₅₁H₂₄₃N₃₉O₃₇
Molecular Weight: 3196.78
Create Date: 2022-06-02 17:08:29
Modify Date: 2025-09-26 20:57:49
CKLF1-C27, a C-terminal peptide of CKLF1, binds to CCR4 receptor and activates ERK1/2 pathway. CKLF1-C27 can abrogate the effect of CKLF1 on cells by competing for CCR4 receptor. CKLF1-C27 shows great effect on promoting proliferation on HUVECs. CKLF1-C27 has the potential for psoriasis research[1].

Name	CKLF1-C27

Description	CKLF1-C27, a C-terminal peptide of CKLF1, binds to CCR4 receptor and activates ERK1/2 pathway. CKLF1-C27 can abrogate the effect of CKLF1 on cells by competing for CCR4 receptor. CKLF1-C27 shows great effect on promoting proliferation on HUVECs. CKLF1-C27 has the potential for psoriasis research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Inflammation/Immunology Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
Target	CCR4 ERK1 ERK2
References	[1]. Yaqi Tan, et al. Chemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis. PLoS One. 2015 Apr 27;10(4):e0125073.

Molecular Formula	C₁₅₁H₂₄₃N₃₉O₃₇
Molecular Weight	3196.78