2762426-00-4

2762426-00-4 structure

Name: Anticancer agent 39
Chemical Name: Anticancer agent 39
CAS Number: 2762426-00-4
Molecular Formula: C₅₀H₆₅N₅O₁₀
Molecular Weight: 896.08
Create Date: 2022-05-20 18:20:33
Modify Date: 2024-01-08 23:55:10
Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].

Name	Anticancer agent 39

Description	Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Chen Zhou, et al. Synthesis, biological evaluation and cellular localization study of fluorescent derivatives of Jiyuan Oridonin A. Eur J Med Chem. 2022 Feb 5;229:114048.

Molecular Formula	C₅₀H₆₅N₅O₁₀
Molecular Weight	896.08